Monday, September 27, 2010

How strongly is inheritance a factor when it comes to scoliosis?

There is some scoliosis in my ancestral: a paternal aunt, who have it so severely that she needed to have a rod inserted when she be in her 20s, and a sister who have a slight-S curve when viewed from the hindmost, as well as an overexaggerated curvature when view from the side. I do not have any curvature whatsoever, and neither do any other siblings or anyone of loving relation. Do I run a large indiscriminate of passing this on to any of my adjectives children? Like many other traits, scoliosis have genetic, prenatal and environmental/acidental causes. The US National Library of Medicine database, OMIM, have three articles on specific types of scoliosis with genetic predisposition.
http://www.ncbi.nlm.nih.gov/entrez/dispo.
http://www.ncbi.nlm.nih.gov/entrez/dispo.
http://www.ncbi.nlm.nih.gov/entrez/dispo.
These articles suggest that the genetic newspaper of scoliosis is a dominant trait. If you do not have any scoliosis, afterwards you probably will not pass it on to brood.
OMIM also says "Scoliosis may go off secondary to other inherent disorders including Marfan syndrome , dysautonomia, neurofibromatosis, Friedreich ataxia, and muscular dystrophies." Other sources list polio, brittle bone disease and other conditions. Mayo say "Scoliosis isn't caused by poor posture, diet, exercise, or the use of backpack."
In the majority of cases, the cause is simply unknown.
Heredity is a especially slim factor in acceptance scoliosis.

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